Title

A new nervogenic acid glycoside with pro-coagulant activity from liparis nervosa

Document Type

Article

Publication details

Song, Q, Shou, Q, Gou, X, Chen, F, Leng, J & Yang, W 2013, 'A new nervogenic acid glycoside with pro-coagulant activity from liparis nervosa', Natural Product Communications, vol. 8, pp. 1-2.

Peer Reviewed

Peer-Reviewed

Abstract

In an effort to identify hemostatic components from Liparis nervosa (Thunb.) Lindl. using a bioactivity-guided fractionation approach, the n-BuOH extract was found to promote ADP-induced platelet aggregation and two compounds were isolated from the active extract. Compound 1 was a new nervogenic acid glycoside and the structure was elucidated as 3,5-bis(3-methyl-but-2-enyl)-4-O-[β-D-xylopyranosyl-(1→2)-β-D-glucopyranosyl]-benzoic acid by extensive spectroscopic measurements. Adenosine (2) was isolated from this plant for the first time. Compound 1 also showed good pro-coagulant activity in vitro.