Title

Associations with asymptomatic colonization with candida in women reporting past vaginal candidiasis: an observational study

Document Type

Article

Publication details

Watson, CJ, Fairley, CK, Grando, D, Garland, SM, Myers, SP & Pirotta, M 2013, 'Associations with asymptomatic colonization with candida in women reporting past vaginal candidiasis: an observational study', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 169, no. 2, pp. 376-379.

Published version available from:

http://dx.doi.org/10.1016/j.ejogrb.2013.03.030

Peer Reviewed

Peer-Reviewed

Abstract

Objective

Asymptomatic vaginal colonization with Candida species is a known risk factor for vulvovaginal candidiasis (VVC). Taking known risk factors for symptomatic VVC, the authors sought to identify factors associated with asymptomatic colonization.

Study design

As part of a randomized controlled trial which compared vaginal candidal colony counts in women taking garlic tablets or placebo, 192 asymptomatic women collected a baseline screening swab for Candida species. Eligibility for this study included at least one self-reported episode of VVC in the previous 12 months and age 18–50 years. Known risk factors for VVC were compared in women colonized with candida and those without colonization.

Results

37% of asymptomatic women who self-reported VVC in the previous 12 months were colonized with vaginal Candida species. Using multivariate analysis, two factors were associated with asymptomatic colonization: a current sexual partner (P = 0.02) and being born outside of Australia (P = 0.05). Use of oral contraceptives was not statistically significant (P = 0.27).

Conclusions

Clinical relevance of asymptomatic colonization with vaginal yeast and its link to episodes of VVC warrants further investigation.