Title

A double-blind, prospective, randomized controlled trial comparing highly cross-linked and conventional polyethylene in primary total hip arthroplasty

Document Type

Article

Publication details

Calvert, GT, Devane, PA, Fielden, J, Adams, K & Horne, JG 209, 'A double-blind, prospective, randomized controlled trial comparing highly cross-linked and conventional polyethylene in primary total hip arthroplasty', The Journal of Arthroplasty, vol. 24, no. 4, pp. 505-510.

Published version available from

http://dx.doi.org/10.1016/j.arth.2008.02.011

Peer Reviewed

Peer-Reviewed

Abstract

Highly cross-linked polyethylene was developed to reduce articular bearing wear in total hip arthroplasty. In vitro studies have shown reduced wear in comparison with conventional polyethylene. A double-blind, prospective, randomized trial was performed comparing highly cross-linked and conventional polyethylene in 119 patients. The primary outcome variables were linear, 3-dimensional, and volumetric wear as determined by analysis of digitized radiographs using validated wear measurement software. Linear, 3-dimensional, and volumetric wear rates were significantly less in the highly cross-linked polyethylene group between 6 months and 4 years postoperatively (P b .05). The data presented here show that highly crosslinked polyethylene reduces short-term polyethylene wear. The intermediate and long-term clinical results of highly cross-linked polyethylene remain unknown pending further follow-up.

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