A novel sulfur-containing diterpenoid from Fritillaria anhuiensis

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Shou, QY, Tan, Q, & Shen, ZW 2009, 'A novel sulfur-containing diterpenoid from Fritillaria anhuiensis', Tetrahedron Letters, vol. 50, no. 28, pp. 4185-4187.

Publisher's version of article available at http://dx.doi.org/10.1016/j.tetlet.2009.05.002

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Two novel diterpenoids were isolated from the bulbs of Fritillaria anhuiensis S. C. Chen and S. E. Yin. Compound 1 was the first diterpenoid containing a sulfonyl group isolated from nature. Compound 2 was a novel kaurane-type diterpenoid. Their structures were determined by extensive spectroscopic analysis (IR, MS, NMR, and X-ray diffraction). Compound 1 significantly attenuated nitric oxide (NO) production of a macrophage cell line of Raw 264.7 cells stimulated with IFN-γ.

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