Associations with asymptomatic colonization with candida in women reporting past vaginal candidiasis: an observational study
Watson, CJ, Fairley, CK, Grando, D, Garland, SM, Myers, SP & Pirotta, M 2013, 'Associations with asymptomatic colonization with candida in women reporting past vaginal candidiasis: an observational study', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 169, no. 2, pp. 376-379.
Published version available from:
Asymptomatic vaginal colonization with Candida species is a known risk factor for vulvovaginal candidiasis (VVC). Taking known risk factors for symptomatic VVC, the authors sought to identify factors associated with asymptomatic colonization.
As part of a randomized controlled trial which compared vaginal candidal colony counts in women taking garlic tablets or placebo, 192 asymptomatic women collected a baseline screening swab for Candida species. Eligibility for this study included at least one self-reported episode of VVC in the previous 12 months and age 18–50 years. Known risk factors for VVC were compared in women colonized with candida and those without colonization.
37% of asymptomatic women who self-reported VVC in the previous 12 months were colonized with vaginal Candida species. Using multivariate analysis, two factors were associated with asymptomatic colonization: a current sexual partner (P = 0.02) and being born outside of Australia (P = 0.05). Use of oral contraceptives was not statistically significant (P = 0.27).
Clinical relevance of asymptomatic colonization with vaginal yeast and its link to episodes of VVC warrants further investigation.